Phantom Limb Pain: Neurobiology, Treatment, And Hope
Received Date: Oct 01, 2025 / Published Date: Oct 29, 2025
Abstract
Phantom limb pain (PLP) is a complex neuropathic pain condition following amputation, linked to central nervous system reorganization. Treatment is multimodal, involving pharmacological agents, physical therapy, and neuromodulation techniques. Research highlights the role of cortical plasticity and stump pain, while therapies like mirror therapy, spinal cord stimulation, and virtual reality show therapeutic potential. Psychological factors are significant, with cognitive-behavioral therapy offering support. Future strategies emphasize personalized approaches and ongoing research.
Keywords: Phantom Limb Pain; Neuropathic Pain; Central Nervous System; Cortical Reorganization; Neuromodulation; Mirror Therapy; Spinal Cord Stimulation; Virtual Reality; Stump Pain; Cognitive Behavioral Therapy
Citation: Müller T (2025) Phantom Limb Pain: Neurobiology, Treatment, And Hope. jpar 14: 786. Doi: 10.4172/2167-0846.1000786
Copyright: © 2025 Thomas Müller This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited
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