Prognostic evaluation of nephroblastoma in Senegal: experience of a regional reference center with 42 cases
Received Date: Dec 01, 2025 / Published Date: Dec 30, 2025
Abstract
To evaluate the epidemiological characteristics, management, and outcomes of nephroblastoma in a regional hospital in Senegal. Methods: Retrospective descriptive and analytical study including 42 patients aged 9 months to 14 years, treated according to the adapted SIOP 2001 protocol between September 2022 and March 2024. Results: The mean age was 3 years and 10 months with a sex ratio of 0.75. The majority of patients (61.9%) came from disadvantaged socioeconomic backgrounds. All patients had a palpable abdominal mass. Preoperative chemotherapy was administered in 97.6% of patients, followed by extended nephrectomy. The intermediate-risk group predominated (78.6%) with stage II in 44% of cases. Overall mortality was 26.2% with 11.9% recurrence. Conclusion: The management of nephroblastoma according to adapted international protocols is feasible in the African context, but socio-economic challenges and diagnostic delays impact prognosis.
Keywords: Nephroblastoma, Wilms tumor, Senegal, Africa, pediatric oncology, SIOP protocol
Citation: Fall M, Yonga D, Nguenegafo G, Malondez G, Seye C, et al. (2025)Prognostic Evaluation of Nephroblastoma in Senegal: Experience of a RegionalReference Center with 42 Cases. J Paediatr Med Sur 9: 359. Doi: 10.4172/jpms.1000359
Copyright: © 2025 Fall M, et al.. This is an open-access article distributed underthe terms of the Creative Commons Attribution License, which permits unrestricteduse, distribution, and reproduction in any medium, provided the original author andsource are credited.
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