Prognostic evaluation of nephroblastoma in Senegal: experience of a regional reference center with 42 cases
Received Date: Dec 01, 2025 / Published Date: Dec 30, 2025
Abstract
Objective: To evaluate the epidemiological characteristics, management, and outcomes of nephroblastoma in a regional hospital in Senegal. Methods: Retrospective descriptive and analytical study including 42 patients aged 9 months to 14 years, treated according to the adapted SIOP 2001 protocol between September 2022 and March 2024. Results: The mean age was 3 years and 10 months with a sex ratio of 0.75. The majority of patients (61.9%) came from disadvantaged socioeconomic backgrounds. All patients had a palpable abdominal mass. Preoperative chemotherapy was administered in 97.6% of patients, followed by extended nephrectomy. The intermediate-risk group predominated (78.6%) with stage II in 44% of cases. Overall mortality was 26.2% with 11.9% recurrence. Conclusion: The management of nephroblastoma according to adapted international protocols is feasible in the African context, but socio-economic challenges and diagnostic delays impact prognosis.
Keywords: Nephroblastoma; Wilms tumor; Senegal; Africa; pediatric oncology; SIOP protocol
Citation: Fall M, Yonga D, Nguenegafo G, Malondez G, Seye C, et al. (2025)Prognostic Evaluation of Nephroblastoma in Senegal: Experience of a RegionalReference Center with 42 Cases. J Paediatr Med Sur 9: 359. Doi: 10.4172/jpms.1000359
Copyright: © 2025 Fall M, et al. This is an open-access article distributed underthe terms of the Creative Commons Attribution License, which permits unrestricteduse, distribution, and reproduction in any medium, provided the original author andsource are credited.
Select your language of interest to view the total content in your interested language
Share This Article
Open Access Journals
Article Tools
Article Usage
- Total views: 139
- [From(publication date): 0-0 - May 24, 2026]
- Breakdown by view type
- HTML page views: 94
- PDF downloads: 45
