Protein Profiling: Advancements for Diagnosis and Therapy
Received Date: Sep 01, 2025 / Published Date: Sep 29, 2025
Abstract
This compilation highlights the remarkable progress in protein profiling methodologies and their broad applications across biological and clinical research. Techniques spanning liquid chromatography-mass spectrometry, multiplexed single-cell analysis, spatial proteomics, and chemical proteomics are discussed. These advancements enable detailed protein quantification, characterization of cellular heterogeneity, and contextual tissue analysis. Key applications include robust biomarker discovery for diseases like cancer and Alzheimer’s, non-invasive diagnostics using biofluids and extracellular vesicles, and elucidation of drug targets. The collective works underscore the increasing precision and utility of protein profiling in enhancing disease understanding and therapeutic strategies.
Keywords: Protein Profiling; Mass Spectrometry; Biomarker Discovery; Single-Cell Proteomics; Spatial Proteomics; Exosomes; Cancer Diagnosis; Alzheimer’s Disease; Liquid Biopsies; Extracellular Vesicles
Citation: El-Hakim S (2025) Protein Profiling: Advancements for Diagnosis and Therapy. jabt 16: 798. Doi: 10.4172/2155-9872.1000798
Copyright: © 2025 Sara El-Hakim This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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