Reducing Organ Ischemia-Reperfusion Injury Through Novel Therapies
Received Date: Jan 02, 2026 / Published Date: Jul 30, 2025
Abstract
This collection of research addresses the critical challenges of organ preservation and ischemia-reperfusion injury (IRI) in transplantation. It explores molecular mechanisms, novel preservation strategies, and therapeutic interventions aimed at mitigating IRI and improving graft outcomes. Key areas include the role of microRNAs, advancements in machine perfusion, mesenchymal stem cell therapy, ex vivo perfusion, and the impact of donor factors, all contributing to a comprehensive understanding of IRI and its management in solid organ transplantation
Keywords: Ischemia-Reperfusion Injury脥戮 Organ Preservation脥戮 Transplantation脥戮 Machine Perfusion脥戮 Stem Cell Therapy脥戮 MicroRNAs脥戮 Endoplasmic Reticulum Stress脥戮 Ex Vivo Lung Perfusion脥戮 Donor Factors脥戮 Organoids
Citation: Markovic E (2025) Reducing Organ Ischemia-Reperfusion Injury Through Novel Therapies. J Clin Exp Transplant 10: 299. Doi: 10.4172/2475-7640.1000299
Copyright: © 2025 Elena Markovic This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited
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