Revolutionizing biology with single-molecule resolution
*Corresponding Author: Dr. Ahmed Y. Al-Harbi, King Faisal University, Faculty of Biochemistry, Saudi Arabia, Email: a.alharbi@kingfaisalbio.sa
Citation: 听听
Copyright: 听听
Abstract
This collection explores the transformative impact of single-molecule techniques in unraveling fundamental biological mechanisms. It highlights diverse applications, from molecular motor mechanics and protein-nucleic acid interactions to RNA-protein complex dynamics and mitochondrial import. The papers also cover viral infection mechanisms, RNA-binding protein behaviors, and membrane protein dynamics in live cells. Crucially, these methods offer real-time insights into CRISPR-Cas DNA repair and molecular events in neurodegenerative diseases. Furthermore, novel single-molecule optical sensing is advancing the detection of epigenetic modifications like DNA methylation, providing unprecedented resolution into complex biological processes for therapeutic and research advancements.
