RNAi Therapeutics: Promise, Challenges, Future
Received Date: May 01, 2025 / Published Date: May 29, 2025
Abstract
RNA interference (RNAi) is a vital gene silencing mechanism that includes siRNAs and miRNAs, critical for regulating gene expression and holding therapeutic promise. Significant progress has been made in RNAi-based therapeutics, targeting previously undruggable genes, with applications in cancer, antiviral strategies, and neurodegenerative diseases. While delivery systems, stability, and off-target effects remain challenges, innovative solutions like nanocarriers and advanced modifications are enhancing efficacy. The combination of RNAi with CRISPR/Cas9 further expands its potential. Continued research focuses on optimizing these technologies for widespread clinical success.
Citation: Al-Sayed DA (2025) RNAi Therapeutics: Promise, Challenges, Future. cmb 71: 390
Copyright: 漏 2025 Dr. Ahmed Al-Sayed This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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