Strategies For Inducing Immune Tolerance In Transplantation
Received Date: Mar 03, 2025 / Published Date: Mar 31, 2025
Abstract
This compilation of research examines diverse strategies to achieve immune tolerance in organ transplantation. It highlights advances in inducing donor-specific hyporesponsiveness, the impact of cellular components like regulatory T cells and exosomes, and the role of the gut microbiome. Emerging therapeutic avenues include CAR-T cells, mesenchymal stem cells, and microRNAs. Furthermore, the influence of costimulatory blockade and immunometabolism on immune responses is explored, aiming to enhance graft acceptance and minimize rejection for improved clinical outcomes
Keywords: Immune Tolerance脥戮 Organ Transplantation脥戮 Donor-Specific Hyporesponsiveness脥戮 Gut Microbiome脥戮 Regulatory T Cells脥戮 Mesenchymal Stem Cells脥戮 CAR-T Cells脥戮 Exosomes脥戮 Immunometabolism脥戮 Costimulatory Blockade
Citation: Kowalska A (2025) Strategies For Inducing Immune Tolerance In Transplantation. J Clin Exp Transplant 10: 274
Copyright: © 2025 Anna Kowalska This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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