Targeted Therapies Revolutionize Endometrial Cancer Treatment
Received Date: Aug 01, 2025 / Published Date: Aug 29, 2025
Abstract
Targeted therapies are transforming endometrial cancer treatment by addressing specific molecular alterations. This includes inhibitors targeting PI3K/AKT/mTOR, HER2, and DNA damage repair pathways, showing promise for advanced/recurrent disease. Molecular profiling is crucial for guiding treatment selection, with ongoing research exploring novel agents and combinations. HER2- targeted therapies and PARP inhibitors are advancing, while immunotherapy combined with targeted agents offers potential benefits. Liquid biopsies and next-generation sequencing aid in personalized treatment and resistance monitoring. Addressing treatment resistance remains a key challenge.
Citation: Clarke DI (2025) Targeted Therapies Revolutionize Endometrial Cancer Treatment. Current Trends Gynecol Oncol 10: 282.
Copyright: 漏 2025 Dr. Isabel Clarke This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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