Understanding and Managing Organ Transplant Rejection
Received Date: Oct 02, 2025 / Published Date: Oct 30, 2025
Abstract
Acute rejection in organ transplantation presents a significant clinical challenge driven by intricate immunological mechanisms. This review syntheses current understanding of the cellular and molecular pathways involved in acute rejection, highlighting diag nostic approaches and emerging interventions. It also covers immunosuppressive therapies, the role of donor-specific antibodies, T cell-mediated rejection, strategies for inducing immune tolerance, the impact of patient non-compliance and the microbiome, and the significance of acute graft vasculopathy. Emphasis is placed on novel therapeutic agents and strategies aimed at improving prevention, treatment, and long-term graft survival.
Citation: Pereira DLM (2025) Understanding and Managing Organ Transplant Rejection. troa 10: 322.
Copyright: 聽漏 2025 Dr. Lucas M. Pereira This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permitsunrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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