Visceral Pain: Mechanisms, Gut-Brain Axis, and Management
Received Date: Jul 01, 2025 / Published Date: Jul 29, 2025
Abstract
This article synthesizes current knowledge on visceral pain, exploring its mechanisms, including neuronal sensitization, neuroinflammation, and glial cell involvement. It examines visceral hypersensitivity in functional gastrointestinal disorders, the role of the enteric nervous system, and the impact of chronic inflammation and the gut microbiome. Therapeutic strategies such as neuromodulation, alongside psychological interventions, are discussed. Advances in neuroimaging and diagnostic challenges are also highlighted, emphasizing a multidisciplinary approach for effective management
Keywords: Visceral Pain脥戮 Neuronal Sensitization脥戮 Neuroinflammation脥戮 Gut Microbiome脥戮 Enteric Nervous System脥戮 Glial Cells脥戮 Gut-Brain Axis脥戮 Neuromodulation脥戮 Functional Gastrointestinal Disorders脥戮 Pain Management
Citation: Popescu DE (2025) Visceral Pain: Mechanisms, Gut-Brain Axis, and Management. J Pain Relief 14: 754. Doi: 10.4172/2167-0846.1000754
Copyright: © 2025 Dr. Elena Popescu This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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