"The existence of connection between codons and the physico-chemical properties of encoded amino acids is well supported by The Common Periodic Table of Codons and Nucleic Acids. This connection suggests co-evolution and possible specific spatial compatibility between codons and amino acids. This question was studied in relation to well-known examples of highly specific protein- nucleic acid interactions provided by restriction endonucleases (RE) and their nucleic acid cut sites (RS). Such studies confirmed that codons and encoded amino acids preferentially co-locate with one another in these structures, suggesting a stereo-chemical connection between nucleic acids and proteins.
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Citation: Biro JC (2014) Suggestion to Upgrade the Canonical Concept of Translation. J Proteomics Bioinform 7: 112-120."
Last date updated on April, 2026