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Protein Degradation: Homeostasis, Stress, and Therapy
Protein degradation pathways, including the ubiquitin-proteasome system (UPS) and autophagy, are fundamental for cellular health and disease. This review explores their intricate mechanisms, from general degradation to specialized processes like mitophagy and ER-associated degradation (ERAD). Cellular stress activates autophagy, while E3 ligases li... Read More»
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10.4172/1165-158X.1000417Abstract Peer-reviewed Article PDF
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